Tautou achieved international recognition for her lead role in the 2001 film Amélie, which met with critical acclaim and was a major box-office success.
Amélie won Best Film at the European Film Awards, four César Awards (including Best Film and Best Director), two BAFTA Awards (including Best Original Screenplay), and was nominated for five Academy Awards.
In 2000, she won the Prix Suzanne Bianchetti as her country's most promising young film actress.
In 2004, she played in A Very Long Engagement, a romantic war film, co-written and directed by Jean-Pierre Jeunet starring Tautou.
In June, she was invited to join the Academy of Motion Picture Arts and Sciences (AMPAS).
In 2005, Tautou starred in her first full Hollywood production, opposite Tom Hanks, in the film version of Dan Brown's best-selling novel The Da Vinci Code, directed by Ron Howard and released in May 2006.
Tautou has since appeared in films in a range of genres, including the thrillers Dirty Pretty Things and The Da Vinci Code, and the romantic Priceless (2006).
She has received critical acclaim for her many roles including the drama A Very Long Engagement (2004) and the biographical drama Coco avant Chanel (2009).